James E. Robinson
Papers
1
Total Citations
112
H-Index
1
About
James E. Robinson is a leading figure in HIV-1 immunology and structural biology, whose work has fundamentally shaped our understanding of the viral envelope glycoprotein gp120. His research focuses on the molecular barriers to antibody neutralization and the development of strategies to overcome them. In a landmark 1999 study (112 citations), Robinson pioneered a probability analysis approach to address the extreme challenges of crystallizing gp120, whose extensive glycosylation and conformational mobility had long thwarted structural studies. This work was instrumental in enabling the first high-resolution structures of the HIV-1 envelope, a breakthrough that transformed vaccine design efforts. Robinson’s contributions have had a lasting impact, providing critical insights into how the virus evades the immune system and guiding the development of broadly neutralizing antibodies. His rigorous, problem-solving approach continues to inspire researchers working at the intersection of virology, immunology, and structural biology.
Research Focus
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Top Papers
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