Ingo Kober
Papers
1
Total Citations
124
H-Index
1
About
Ingo Kober is a molecular biologist recognized for pioneering high-throughput approaches to map protein-protein interaction networks, particularly those governing nuclear receptor signaling. His most cited work, "Automated Yeast Two-hybrid Screening for Nuclear Receptor-interacting Proteins" (2004, 124 citations), established a cornerstone methodology for systematically identifying cofactors that modulate gene expression. By developing and automating the yeast two-hybrid system, Kober enabled the large-scale, unbiased discovery of novel interactions between nuclear receptors and their regulatory partners—a critical step in understanding hormone signaling, metabolism, and disease. This technical innovation transformed hypothesis-generating research, allowing labs to move beyond single-protein studies to comprehensive interactome mapping. His contributions have directly impacted fields ranging from endocrinology to cancer biology, providing a foundational toolkit for researchers exploring transcriptional regulation. Kober’s work exemplifies how method development can accelerate biological discovery, and his automated screening platform remains a reference point for modern proteomic interaction studies.
Research Focus
Key Achievements
Top Papers
- 1Automated Yeast Two-hybrid Screening for Nuclear Receptor-interacting Proteins124 citations · 2004