Harald Kranz

Papers

Total Citations

124

H-Index

About

Harald Kranz is a molecular biologist whose work has significantly advanced the high-throughput analysis of protein-protein interactions, with a particular focus on nuclear receptor signaling. His most influential contribution, the 2004 paper "Automated Yeast Two-hybrid Screening for Nuclear Receptor-interacting Proteins," has garnered 124 citations and established a foundational methodology for systematic interactome mapping. By developing an automated, improved version of the classic yeast two-hybrid system, Kranz enabled the large-scale screening of nuclear receptors and their cofactors—proteins central to gene regulation, metabolism, and disease. This work transformed hypothesis-generating research, allowing scientists to move beyond single-interaction studies to comprehensive network analyses. Kranz’s innovations have had a lasting impact on the field, providing a robust platform for discovering novel receptor-interacting proteins and accelerating drug target identification. His contributions remain essential reading for researchers exploring the complex regulatory networks that govern cellular function, making him a key figure in the evolution of functional genomics and interactomics.