Hirohisa Ohno
Papers
2
Total Citations
129
H-Index
2
About
Hirohisa Ohno is a pioneer at the intersection of RNA nanotechnology and synthetic biology, where his work focuses on engineering functional RNA–protein (RNP) complexes for imaging and therapeutic applications. His landmark 2014 study (79 citations) demonstrated the construction of RNA–protein complexes with programmable shapes, laying the groundwork for molecular robotics and nanomedicine by enabling direct visualization of functional RNP nanostructures in living cells. Building on this, his 2017 work (50 citations) achieved a major breakthrough: the first protein-driven RNA nanostructured devices capable of controlling mammalian cell fate. These devices detect and amplify specific protein signals, then trigger precise cellular responses—a critical step toward smart therapeutics. Ohno’s contributions are notable for bridging structural RNA design with functional biological control, offering a platform for next-generation nanodevices that operate inside living systems. His research has profound implications for synthetic biology, targeted drug delivery, and regenerative medicine, establishing him as a leading figure in the emerging field of RNA-based molecular machinery.
Research Focus
Key Achievements
Top Papers
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