Hans J. Jansen
Papers
3
Total Citations
105
H-Index
2
About
Hans J. Jansen is a pioneering researcher at the intersection of bioengineering and infectious disease immunology, with a primary focus on zebrafish models for high-throughput biomedical screening and tuberculosis research. His most influential work, "Robotic injection of zebrafish embryos for high-throughput screening in disease models" (2013, 99 citations), revolutionized the field by automating microinjection into zebrafish larvae, enabling scalable, reproducible drug and genetic screens for human disease models. This technical breakthrough has become a cornerstone for laboratories studying developmental biology and host-pathogen interactions. More recently, Jansen has made critical contributions to tuberculosis research, demonstrating that the human pathogen *Mycobacterium tuberculosis* and the fish pathogen *Mycobacterium marinum* trigger a shared core set of late innate immune response genes in zebrafish larvae (2024, 4 and 2 citations). By leveraging zebrafish as a natural host for mycobacteria, his work provides a powerful, transparent in vivo model to dissect conserved immune mechanisms, bridging basic science and translational applications. Jansen’s achievements highlight his dual impact: advancing robotic automation in model organism research and uncovering fundamental immune responses to major human pathogens.
Research Focus
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