Annemarie H. Meijer

About

Annemarie H. Meijer is a pioneering researcher in infectious disease biology, best known for establishing the zebrafish larva as a powerful surrogate model for tuberculosis research. Her work bridges the gap between high-throughput technology and host-pathogen immunology, with a particular focus on *Mycobacterium tuberculosis* and its close relative, *Mycobacterium marinum*. Meijer’s major contributions include developing a high-throughput screening system for tuberculosis progression (126 citations) and pioneering a robotic injection method for zebrafish embryos (99 citations), enabling rapid, scalable analysis of disease models. Her recent studies have revealed that *M. tuberculosis* and *M. marinum* trigger a core set of late innate immune response genes in zebrafish larvae, a finding with profound implications for understanding conserved host defenses. By merging automation with whole-organism biology, Meijer has overcome a critical bottleneck in tuberculosis drug discovery, offering new avenues for combating multi-drug resistant strains. Her work is widely cited and continues to shape the future of infectious disease research.

Research Focus

Key Achievements

Top Papers

1. 1
   A High-Throughput Screen for Tuberculosis Progression

   126 citations · 2011
2. 2
   Robotic injection of zebrafish embryos for high-throughput screening in disease models

   99 citations · 2013
3. 3
   The Human Pathogen Mycobacterium tuberculosis and the Fish Pathogen Mycobacterium marinum Trigger a Core Set of Late Innate Immune Response Genes in Zebrafish Larvae

   4 citations · 2024
4. 4
   The human pathogen <i>Mycobacterium tuberculosis</i> and the fish pathogen <i>Mycobacterium marinum</i> trigger the same core set of late innate immune response genes in zebrafish larvae

   2 citations · 2024

Key Collaborators

Contact & Links