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About

Gianluca Vago is a pioneering urologic surgeon and researcher whose work is transforming the precision of prostate cancer surgery. His primary research focuses on intraoperative imaging and surgical navigation, specifically the use of advanced technologies to improve outcomes in robot-assisted radical prostatectomy (RARP). Vago’s major contributions center on evaluating and validating novel methods for real-time margin assessment during surgery. His landmark 2024 study, with 14 citations, demonstrated that ex vivo fluorescence confocal microscopy (FCM) performs comparably to intra-operative frozen section analysis for evaluating surgical margins, using final pathology as the gold standard. This work has significant implications for reducing positive surgical margins and improving cancer control. Vago is also leading a phase 3 prospective randomized trial—a notable achievement in surgical oncology—to investigate whether augmented reality and augmented reality frozen section analysis can further reduce positive margin rates. His research bridges the gap between cutting-edge imaging technology and clinical practice, offering a path toward more precise, nerve-sparing surgery. With his innovative trial protocols and rigorous comparative studies, Vago is at the forefront of integrating digital and augmented reality tools into the operating room, directly impacting patient outcomes in prostate cancer care.