Giancarlo Pascali
Papers
1
Total Citations
33
H-Index
1
About
Giancarlo Pascali is a leading figure in molecular imaging and radiochemistry, whose work bridges the gap between advanced neuroimaging and real-world animal behavior. His primary research focuses on developing novel positron emission tomography (PET) methodologies, particularly for studying brain function in freely moving subjects. Pascali’s most notable contribution is the pioneering "Open-field PET" system, which enables simultaneous brain functional imaging and behavioral response measurements in freely moving small animals. This breakthrough, detailed in his highly cited 2018 paper (33 citations), overcomes the limitations of traditional anesthesia-based PET scans, allowing researchers to observe authentic neural activity during naturalistic behaviors. By integrating radiochemistry with innovative scanner design, Pascali has opened new avenues for studying neuropsychiatric disorders, drug effects, and cognitive processes in ecologically valid conditions. His work has been instrumental in advancing preclinical imaging, with his open-field approach now adopted by laboratories worldwide. Pascali’s achievements include multiple patents and collaborations with leading neuroscience centers, cementing his reputation as a transformative innovator in translational neuroimaging.
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