Georgios I. Angelis

Papers

Total Citations

H-Index

About

Georgios I. Angelis is a pioneer in preclinical neuroimaging, specializing in the development of motion-compensated positron emission tomography (PET) for awake, unrestrained animals. His groundbreaking work eliminates the need for anesthetics, which can confound neurological and behavioral studies, by enabling simultaneous brain functional imaging and behavioral response measurements in freely moving subjects. Angelis’s most cited paper, “Markerless Motion Tracking of Awake Animals in Positron Emission Tomography” (2014, 49 citations), introduced a noninvasive method to track and correct for motion during PET scans, allowing researchers to study an animal’s natural behavioral responses to stimuli or administered drugs in real time. His subsequent work, “Open-field PET” (2018, 33 citations), further advanced this paradigm by integrating imaging with open-field behavioral assays, offering an unprecedented window into the neural correlates of spontaneous behavior. With a career focused on bridging imaging technology and ethologically relevant experimental designs, Angelis has made transformative contributions to functional neuroimaging, enabling more accurate, translational studies of brain function and drug effects. His innovations continue to shape preclinical neuroscience, providing tools that respect animal welfare while unlocking new dimensions of brain-behavior research.