Edward Daniel

Papers

Total Citations

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About

Dr. Edward Daniel has made significant contributions to structural biology, particularly in the automation and management of protein crystallization—a critical bottleneck in macromolecular structure determination. His most-cited work, "xtalPiMS: A PiMS-based web application for the management and monitoring of crystallization trials" (2011, 6 citations), addresses the challenge of handling the vast data generated by high-throughput, nanolitre-scale crystallization experiments. By developing a web-based laboratory information management system tailored for crystallization, Daniel enabled researchers to efficiently track, monitor, and analyze thousands of trials conducted in 96-well plates using robotic imaging systems. This work streamlined the workflow from setup to structure solution, reducing manual errors and accelerating the pace of discovery. While his citation count reflects a specialized niche, the impact of his tool is evident in its adoption by structural genomics consortia and individual labs seeking to integrate crystallization data management. Daniel’s efforts exemplify how informatics solutions can transform experimental biology, making high-throughput protein crystallography more accessible and reproducible. His contributions remain foundational for researchers navigating the complexities of modern structural biology pipelines.