Colleen K. Van Pelt
Papers
2
Total Citations
20
H-Index
2
About
Colleen K. Van Pelt is a pioneering analytical chemist whose work has significantly advanced the field of liquid chromatography-mass spectrometry (LC-MS) instrumentation. Her research focuses on developing novel interfaces and methodologies that improve the sensitivity, reproducibility, and automation of mass spectrometric analysis. Van Pelt's most notable contribution is the development and characterization of the first vendor-neutral, ultra-high pressure-compatible (∼10,000 p.s.i.) LC-MS source that automates connections between capillary traps, columns, and emitters. This "plug and play" innovation, detailed in her 2013 paper (7 citations), represents a major step forward in reducing variability and user error in complex LC-MS workflows. Earlier, her work on determining SCH 211803 by nanoelectrospray infusion mass spectrometry (2004, 13 citations) provided critical insights into matrix effects, comparing this technique directly with traditional LC-MS/MS. While her citation counts reflect a specialized but impactful career, Van Pelt's true legacy lies in her engineering contributions that have made high-performance LC-MS more accessible and reliable for the broader scientific community, particularly in pharmaceutical and bioanalytical applications.
Research Focus
Key Achievements
Top Papers
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