Chongyun Cheng
Papers
1
Total Citations
8
H-Index
1
About
Chongyun Cheng is a structural biologist whose work illuminates the molecular architecture of life, with a particular focus on proteins from extremophilic organisms. His research centers on X-ray crystallography and the development of innovative phasing methods to solve protein structures, especially those lacking sequence homology to known folds. His most notable contribution is the determination of the crystal structure of AF1514, a novel non-Pfam protein from the hyperthermophilic archaeon *Archaeoglobus fulgidus*. This work, published in 2008, was groundbreaking for its use of the single-wavelength anomalous dispersion (S-SAD) technique with a chromium X-ray source, demonstrating a powerful approach for solving structures of proteins with no detectable sequence similarity to known entries. While his most-cited paper has garnered 8 citations, its methodological significance is profound, showcasing a path forward for structural genomics on challenging, "orphan" proteins. Cheng’s achievements highlight a career dedicated to pushing the technical boundaries of structural biology, enabling the visualization of unique protein folds and providing insights into the molecular strategies of life in extreme environments.
Research Focus
Key Achievements
Top Papers
- 1