Candace S. Johnson
Buffalo State University, Roswell Park Comprehensive Cancer Center
Papers
3
Total Citations
61
H-Index
3
About
Candace S. Johnson is a leading urologic oncology researcher whose work bridges tumor biology, epigenetics, and surgical outcomes in bladder and prostate cancers. Her research focuses on how the tumor microenvironment—particularly the epigenetic regulation of endothelial cells—influences cancer progression. In a highly cited 2011 study (32 citations), Johnson demonstrated that differential methylation of the CYP24A1 gene promoter distinguishes endothelial cells from benign versus malignant prostate tissue, revealing how epigenetic alterations in tumor-associated vasculature contribute to the microenvironment’s malignant transformation. This work has implications for understanding vitamin D metabolism in cancer and identifying vascular targets. Johnson also made significant contributions to bladder cancer recurrence research, notably developing a method to accurately quantify residual cancer cells in pelvic washings following robot-assisted radical cystectomy. Her 2019 study (26 citations) showed that this quantification is associated with cancer recurrence, offering a potential prognostic tool. Her provocative 2016 work (3 citations) critically questioned whether tumor dissemination during robotic cystectomy is truly minimized, challenging conventional surgical wisdom. Johnson’s research has advanced our understanding of how epigenetic changes in the tumor microenvironment and surgical technique impact cancer outcomes, with her work cited over 60 times across key studies.
Research Focus
Key Achievements
Top Papers
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