Papers
2
Total Citations
36
H-Index
2
About
Wiam Bshara’s research lies at the intersection of cancer epigenetics and tumor microenvironment biology, with a particular focus on prostate cancer. Her most cited work investigates how epigenetic alterations—specifically DNA methylation of the *CYP24A1* gene—differ between endothelial cells isolated from malignant versus benign prostate tissue. This pioneering study, which has garnered 32 citations, revealed that the tumor microenvironment drives distinct epigenetic programming in its associated vasculature, offering new insights into how tumors co-opt normal blood vessels for growth and progression. Bshara’s work highlights that epigenetic changes are not confined to cancer cells alone but extend to the surrounding stromal and endothelial compartments. In a related study, she examined the impact of surgical devascularization time on tissue quality in robot-assisted laparoscopic radical prostatectomy (RALP), demonstrating that minimizing ischemic time is critical for preserving RNA integrity and cell viability in procured tissues. This methodological contribution underscores her commitment to rigorous tissue handling protocols that underpin reliable translational research. Through these contributions, Bshara has advanced our understanding of the epigenetic landscape of the tumor microenvironment and the practical challenges of prostate cancer tissue research.
Research Focus
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Top Papers
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