Metabolic engineering

Automated multiplex genome-scale engineering in yeast

Tong Si, Ran Chao, Yuhao Min, Yuying Wu, Wen Ren, Huimin Zhao

Citations: 201 • 2017

MACBETH: Multiplex automated Corynebacterium glutamicum base editing method

Yu Wang, Ye Liu, Jiao Liu, Yanmei Guo, Liwen Fan, Xiaomeng Ni, Xiaomei Zheng, Meng Wang, Ping Zheng, Jibin Sun, Yanhe Ma

Citations: 184 • 2018

Metabolic Engineering of ω3-Very Long Chain Polyunsaturated Fatty Acid Production by an Exclusively Acyl-CoA-dependent Pathway

Mareike D. Hoffmann, Martin Wagner, Amine Abbadi, Martin Fulda, Ivo Feußner

Citations: 103 • 2008

Controlling cell-free metabolism through physiochemical perturbations

Ashty S. Karim, Jacob T. Heggestad, Samantha A. Crowe, Michael C. Jewett

Citations: 82 • 2017

Accelerating strain engineering in biofuel research via build and test automation of synthetic biology

Jianzhi Zhang, Yongcan Chen, Lihao Fu, Erpeng Guo, Bo Wang, Lei Dai, Tong Si

Citations: 68 • 2021

A novel platform for automated high-throughput fluxome profiling of metabolic variants

Stéphanie Heux, Juliette Poinot, Stéphane Massou, Sergueï Sokol, Jean‐Charles Portais

Citations: 37 • 2014

An automated pipeline for the screening of diverse monoterpene synthase libraries

Nicole G. H. Leferink, Mark S. Dunstan, Katherine A. Hollywood, Neil Swainston, Andrew Currin, Adrian J. Jervis, Eriko Takano, Nigel S. Scrutton

Citations: 37 • 2019

Directed evolution of biofuel-responsive biosensors for automated optimization of branched-chain alcohol biosynthesis

Maximilian Ole Bahls, Lukas Platz, Gaspar Morgado, Gregor W. Schmidt, Sven Panke

Citations: 33 • 2021

Technological advancement spurs Komagataella phaffii as a next-generation platform for sustainable biomanufacturing

Le Gao, Jie Yuan, Kai Hong, Nyuk Ling, Shuguang Liu, Xin Wu

Citations: 20 • 2025

Robotic workflows for automated long-term adaptive laboratory evolution: improving ethanol utilization by Corynebacterium glutamicum

Lars Halle, Niels Hollmann, Niklas Tenhaef, Lea Mbengi, Christiane Glitz, Wolfgang Wiechert, Tino Polen, Meike Baumgart, Michael Bott, Stephan Noack

Citations: 15 • 2023

Automated and Programmable Cell-Free Systems for Scalable Synthetic Biology with a Focus on Biofoundry Integration

Ji-Su Jun, Sujin Hong, Jun Hong Park, Jonghyeok Shin, Dae‐Hee Lee

Citations: 3 • 2025