Ye Che

Pfizer (United States)

Papers

1

Total Citations

7

H-Index

1

About

Ye Che is a prominent researcher in the fields of drug metabolism and high-throughput screening, with a focus on developing innovative tools to accelerate pharmaceutical discovery. Their most notable contribution is the design of a novel multiplexed high-throughput screening platform for identifying selective inhibitors of drug-metabolizing enzymes directly within human hepatocytes—a breakthrough that bridges the gap between in vitro assays and physiological relevance. This work, published in 2024 and already garnering 7 citations, demonstrates Che’s ability to address critical bottlenecks in early-stage drug development by enabling rapid, simultaneous profiling of enzyme inhibition. The approach not only enhances the efficiency of lead optimization but also reduces the reliance on animal models, aligning with modern principles of translational science. Che’s research has significant implications for predicting drug-drug interactions and improving safety assessments, marking them as a rising authority in their domain. Their achievements highlight a commitment to merging cutting-edge methodology with practical applications, making their work essential reading for students and researchers in pharmacology and chemical biology.

Research Focus

Key Achievements

1
H-Index
1
Papers
7
Total Citations
7
Avg Citations/Paper
🏆 Most Cited Paper
Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes
7 citations · 2024
📈 Most Prolific Year: 2024 (1 Papers)
🤝 Key Collaborators: 11
🏛 Institutions: Pfizer (United States)

Top Papers

  1. 1

Key Collaborators

Contact & Links

Available for collaboration
Content generated · 11 days ago