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Novel Multiplexed High Throughput Screening of Selective Inhibitors for Drug-Metabolizing Enzymes Using Human Hepatocytes

Jianhua Liu, Daria I. Vernikovskaya, Gary Bora, Anthony Carlo, Woodrow Burchett, Samantha Jordan, Lloyd Wei Tat Tang, Joy C. Yang, Ye Che, George Chang, Matthew D. Troutman, Li Di

Year
2024
Citations
7

Keywords

High-throughput screeningEnzymeCytochrome P450Aldehyde oxidaseDrugDrug discoveryErlotinibComputational biologyVirtual screeningEnzyme inhibition

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