Papers
3
Total Citations
248
H-Index
3
About
Steven W. Taylor is a leading biochemist whose research focuses on mitochondrial biology, proteomics, and metabolic disease. His major contributions center on developing innovative methods to study the mitochondrial proteome and the NADH dehydrogenase complex (Complex I), a critical component of the electron transport chain. Taylor’s landmark 2003 paper, with 108 citations, introduced a rapid one-step immunopurification technique to isolate human NADH dehydrogenase, directly linking defects in this complex to mitochondrial diseases and late-onset neurological disorders like Parkinson’s disease. In 2002, he pioneered an alternative strategy for mitochondrial proteomics using sucrose gradient fractionation and 1D PAGE on highly purified human heart mitochondria (83 citations), offering a powerful complement to traditional 2D PAGE approaches. More recently, Taylor developed a high-throughput mass spectrometry assay to simultaneously measure intact insulin and C-peptide (57 citations), advancing diabetes research. His work has been instrumental in providing tools and insights that bridge mitochondrial dysfunction with human pathology, earning him recognition as a key figure in mitochondrial medicine and proteomics.
Research Focus
Key Achievements
Top Papers
- 1
- 2
- 3