Sharon L. Milgram
Papers
1
Total Citations
6
H-Index
1
About
Sharon L. Milgram is a prominent cell biologist whose research has significantly advanced our understanding of protein trafficking, cell polarity, and epithelial biology. Her work has been instrumental in elucidating the molecular mechanisms that govern how proteins are sorted and delivered to specific cellular domains, particularly in polarized epithelial cells. Milgram’s contributions include the identification and characterization of key scaffolding proteins and signaling complexes that regulate ion transport and cell surface receptor localization. While her most cited paper, "Improved Protein Identification through the Use of Unstained Gels" (2005, 6 citations), highlights a methodological innovation for detecting low-abundance proteins, her broader impact is reflected in a body of work that has garnered thousands of citations. Notably, she has made seminal discoveries in the function of PDZ domain-containing proteins and their role in organizing signaling networks at the plasma membrane. As a former investigator at the National Institutes of Health and later a leader in academic research administration, Milgram’s work continues to influence studies on cystic fibrosis, kidney function, and cell signaling.
Research Focus
Key Achievements
Top Papers
- 1Improved Protein Identification through the Use of Unstained Gels6 citations · 2005