Sasa Mutic

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About

Sasa Mutic is a leading figure in proton therapy and radiation oncology physics, with a career focused on translating advanced imaging and delivery technologies into clinical practice. His key research areas include proton therapy system commissioning, adaptive radiotherapy, and image-guided treatment. Mutic’s major contributions are exemplified by his work on the first clinical gantry-mounted proton therapy system, where he led the comprehensive commissioning and initial clinical implementation of the Mevion S250 platform at the S. Lee Kling Proton Therapy Center. This foundational study, with 36 citations, established protocols for single-room proton therapy that have been adopted globally. He also pioneered the use of mobile helical CT scanners to guide adaptive proton therapy, a concept detailed in his 2018 paper (18 citations) that addresses the critical challenge of anatomical changes during treatment. Beyond these publications, Mutic has been instrumental in shaping clinical workflows and safety standards for proton therapy, earning recognition as a thought leader in medical physics. His work continues to influence how proton centers integrate imaging and delivery systems, improving precision and patient outcomes in radiation oncology.