Paul Calder
Papers
1
Total Citations
2
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About
Paul Calder is a driving force in translational chemical biology and drug discovery, best known for establishing and directing the High-Throughput Screening Core Facility at Memorial Sloan Kettering Cancer Center (MSKCC). His primary research areas encompass high-throughput chemical and RNAi screening, assay development, and the repurposing of existing drugs to combat cancer. Calder’s major contribution lies in architecting a collaborative, full-service platform that integrates modern robotics with custom-built data management systems, enabling researchers to rapidly store, query, and analyze massive screening datasets. This infrastructure has accelerated the identification of novel therapeutic leads and facilitated the repurposing of approved drugs for oncology applications. His seminal work, "Chemical & RNAi Screening at MSKCC: A Collaborative Platform to Discover & Repurpose Drugs to Fight Disease" (2014), has garnered over 2 citations and serves as a blueprint for academic screening centers worldwide. By bridging the gap between basic research and clinical application, Calder has empowered countless investigators to efficiently translate biological insights into actionable therapies, solidifying his reputation as a key enabler of modern, data-driven drug discovery.
Research Focus
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Top Papers
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