Mina Kalantari‐Dehaghi
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1
Total Citations
421
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1
About
Mina Kalantari‐Dehaghi has made transformative contributions to immunoproteomics and infectious disease research, particularly through the development of high-throughput platforms for antigen discovery. Her landmark 2005 work, cited over 420 times, introduced a powerful proteome microarray system that overcame a critical bottleneck in the post-genomic era: the efficient production and screening of complete pathogen proteomes. By engineering a high-throughput PCR recombination cloning and expression platform, she enabled the rapid, batch-processing of hundreds of genes, allowing researchers to profile the humoral immune response to infection on an unprecedented scale. This innovation not only accelerated the identification of novel vaccine candidates and diagnostic antigens but also provided a systematic framework for understanding host-pathogen interactions. Her work has had lasting impact on the fields of vaccinology and serodiagnosis, offering a scalable solution that has been adapted for studying a wide range of human pathogens. Kalantari‐Dehaghi’s research exemplifies how creative technological development can directly address fundamental challenges in translational immunology, making her a key figure in the advancement of proteome-based immune profiling.
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