Jenny E. Hernandez

Papers

Total Citations

421

H-Index

About

Dr. Jenny E. Hernandez has made pioneering contributions to infectious disease immunology and vaccinology, with a career distinguished by the development of high-throughput platforms for antigen discovery. Her most-cited work, the 2005 study "Profiling the humoral immune response to infection by using proteome microarrays," has garnered over 420 citations and remains a cornerstone in the field. In this landmark paper, Dr. Hernandez and her team addressed a critical bottleneck in post-genomic research by creating a high-throughput PCR recombination cloning and expression platform that enables the batch processing of hundreds of genes. This innovation allowed for the rapid production of complete proteomes, facilitating the systematic profiling of humoral immune responses to infection. Her work has directly accelerated the discovery of vaccine and diagnostic antigens, providing a powerful tool for combating emerging pathogens. By bridging the gap between genomic sequence data and functional proteomics, Dr. Hernandez has fundamentally advanced our ability to understand host-pathogen interactions, making her a key figure in the rational design of next-generation vaccines and immunodiagnostics.