L. Cecilia
Papers
1
Total Citations
92
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1
About
Dr. L. Cecilia is a pioneering figure in high-throughput bioanalysis, whose work has dramatically accelerated the pace of pharmaceutical and biomedical research. Her key contributions lie at the intersection of automated sample preparation and ultra-fast liquid chromatography-tandem mass spectrometry (LC-MS/MS). In her landmark 2002 paper, cited over 90 times, she introduced a revolutionary system capable of extracting and analyzing 1152 plasma samples in just 10 hours—achieving a throughput of 30 seconds per sample. This was accomplished by ingeniously integrating a Zymark track robot with a Tecan Genesis liquid handler for parallel solid-phase extraction, coupled with high-speed gradient LC-MS/MS. This work fundamentally redefined the limits of bioanalytical speed and efficiency, enabling unprecedented large-scale pharmacokinetic and toxicokinetic studies. Dr. Cecilia’s innovations have become foundational for modern drug development, where rapid, reliable quantification of drugs and metabolites in biological matrices is critical. Her legacy is a testament to how engineering automation and analytical chemistry can solve real-world bottlenecks in life sciences.
Research Focus
Key Achievements
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