Timothy Olah
Papers
1
Total Citations
92
H-Index
1
About
Timothy Olah is a leading figure in bioanalytical chemistry, renowned for pioneering ultra-high-throughput liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods. His core research focuses on accelerating bioanalysis through the integration of automated sample preparation, high-speed chromatography, and mass spectrometry, directly addressing the critical need for rapid pharmacokinetic screening in drug discovery. Olah’s most impactful contribution is the development of a fully automated, high-speed gradient parallel LC-MS/MS system capable of processing a plasma sample every 30 seconds. This landmark work, which has garnered 92 citations, demonstrated the extraction and analysis of 1,152 plasma samples within just 10 hours by seamlessly integrating a Zymark track robot with a Tecan Genesis liquid handler for simultaneous solid-phase extraction. By slashing analysis times from minutes to seconds without compromising data quality, Olah’s innovations have fundamentally reshaped bioanalytical workflows, enabling unprecedented throughput for preclinical and clinical studies. His achievements stand as a benchmark for efficiency in modern pharmaceutical analysis.
Research Focus
Key Achievements
Top Papers
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