Jacquelyn MacDonell
Papers
2
Total Citations
85
H-Index
2
About
Jacquelyn MacDonell is a pioneering researcher in the field of interventional neuro-oncology, specializing in the development of minimally invasive thermal ablation techniques for brain tumors and epilepsy. Her work centers on magnetic resonance–guided focused ultrasound (MRgFUS), particularly the innovative interstitial approach (iMRgFUS), which delivers high-intensity focused ultrasound directly into the tumor via a robotic-assisted probe. This method offers a compelling alternative to conventional treatments like resection, chemotherapy, and laser interstitial thermal therapy (LITT), as it avoids thermal tissue charring and can produce larger, more controlled ablations. Her most-cited paper, “Magnetic resonance–guided interstitial high-intensity focused ultrasound for brain tumor ablation” (2018), has garnered 63 citations, underscoring its influence in advancing non-invasive neurosurgery. In a related study using a swine model (2018, 22 citations), she demonstrated the feasibility of robotic-assisted MRI-guided iMRgFUS, paving the way for clinical translation. MacDonell’s contributions are shaping the future of targeted brain therapy, offering new hope for patients with inoperable lesions.
Research Focus
Key Achievements
Top Papers
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