Igor Polikarpov
Papers
1
Total Citations
7
H-Index
1
About
Igor Polikarpov is a leading structural biologist whose research centers on the molecular mechanisms of cellulolytic enzymes, with a particular focus on biomass degradation for bioenergy applications. His major contributions lie in elucidating the three-dimensional structures of key cellulases from filamentous fungi, especially those from *Trichoderma harzianum*, a species renowned for its potent cellulolytic activity. Polikarpov’s work on the catalytic domain of the extracellular cellulase CBHI has been foundational, providing critical insights into how these enzymes hydrolyze microcrystalline cellulose—a process essential for converting plant biomass into fermentable sugars. By purifying, crystallizing, and solving the preliminary crystallographic structure of this enzyme, he has helped pave the way for rational engineering of more efficient cellulases. His studies, which have garnered citations in the field, underscore the importance of structural biology in advancing renewable energy technologies. Polikarpov’s research not only deepens our understanding of fungal enzyme systems but also holds promise for improving industrial processes in biofuel production and sustainable chemistry.
Research Focus
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Top Papers
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