Hajime Sui
Papers
1
Total Citations
7
H-Index
1
About
Hajime Sui is a leading figure in genetic toxicology, whose work has significantly advanced the efficiency and scalability of genotoxicity screening. His primary research focuses on the development and refinement of high-throughput bacterial mutagenicity assays, particularly the fluctuation Ames test. Sui’s most notable contribution is the improvement and evaluation of a high-throughput version of this test using 384-well plates with *Salmonella typhimurium* strains TA100 and TA98. This innovation, detailed in his 2009 paper, directly addressed the growing need for rapid, miniaturized screening methods in drug discovery, allowing for the evaluation of compounds with minimal sample volume. By adapting the traditional Ames test to a high-density format, Sui enabled faster, more cost-effective genotoxicity assessment, a critical step in early-stage pharmaceutical development. His work has garnered 7 citations, reflecting its targeted impact on the field of toxicological screening. Sui’s contributions are essential for researchers seeking to balance thorough safety evaluation with the high-throughput demands of modern drug discovery pipelines.
Research Focus
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Top Papers
- 1