Ferid Murad
Papers
1
Total Citations
48
H-Index
1
About
Ferid Murad is a pioneering figure in cell signaling whose work revolutionized our understanding of how nitric oxide (NO) operates in the body. His key research areas include the NO/cGMP signaling pathway, soluble guanylyl cyclase (sGC) regulation, and the molecular mechanisms of vasodilation. Murad’s seminal discovery that nitric oxide acts as a signaling molecule in the cardiovascular system earned him the Nobel Prize in Physiology or Medicine in 1998. His most-cited work, including the 2008 study on α1 sGC splice forms, explores the structural and functional diversity of sGC, a central effector in NO signaling. This research has profound implications for understanding blood pressure regulation, platelet function, and neurotransmission. With over 48 citations on this specific paper alone, Murad’s contributions have shaped modern pharmacology, leading to the development of drugs like nitroglycerin and sildenafil. His legacy endures as a cornerstone of vascular biology and therapeutic innovation.
Research Focus
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Top Papers
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