Elizabeth Brese

Roswell Park Comprehensive Cancer Center

Papers

Total Citations

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About

Elizabeth Brese is a translational researcher whose work focuses on optimizing tissue quality for prostate cancer research. Her key contributions center on the critical pre-analytical variables that affect biospecimen integrity, particularly in the context of robot-assisted laparoscopic radical prostatectomy (RALP). In her most cited work, "Impact of devascularization and tissue procurement on cell number and RNA integrity in prostatectomy tissue" (2015, 4 citations), Brese systematically examined how intra-operative timing—specifically the interval between tissue devascularization and procurement—influences two essential indicators of tissue quality: cell number and RNA integrity. This foundational study provides practical guidance for surgical teams and biobank personnel, ensuring that prostatectomy specimens yield the highest-quality molecular data for downstream research. By establishing evidence-based protocols for tissue handling, Brese has helped strengthen the reliability of prostate cancer biomarker studies. Her work underscores the importance of standardized procurement procedures in translational oncology, making her a valuable contributor to the field of biospecimen science and precision medicine.