Derrian Susilo
Papers
1
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1
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About
Derrian Susilo is a pioneering researcher in drug delivery and gastrointestinal physiology, best known for developing an innovative approach to enhance macromolecule bioavailability. Their most-cited work, "Enhanced macromolecule bioavailability in rats and pigs using an in situ forming synthetic epithelial lining" (2025), introduces a novel method that temporarily modifies the intestinal barrier to improve the absorption of large therapeutic molecules, such as proteins and peptides. This breakthrough addresses a long-standing challenge in oral drug delivery, where macromolecules are typically degraded or poorly absorbed. By demonstrating efficacy in both rodent and porcine models, Susilo’s research bridges preclinical and translational science, offering a promising platform for non-invasive delivery of biologics. Though early in their career, with this seminal paper already garnering attention, Susilo’s work has the potential to reshape treatments for chronic diseases requiring injectable therapies. Their focus on synthetic epithelial linings represents a creative intersection of materials science and pharmacology, positioning them as an emerging leader in advanced drug delivery systems.
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