Charles G. Bailey
Papers
1
Total Citations
34
H-Index
1
About
Charles G. Bailey has made pivotal contributions to bioprocess engineering and recombinant protein production, particularly through the development of high-throughput methods for mammalian cell line development. His most cited work introduces a novel approach using a metallothionein-GFP fusion protein as a dominant selectable and amplifiable marker, enabling rapid, fluorescence-based clonal selection of high-producing recombinant CHO cells. This innovation dramatically reduces the time traditionally required for isolating stable, high-yield clones—a critical bottleneck in producing therapeutic proteins. With 34 citations, this paper has influenced industrial and academic bioprocessing strategies, streamlining the path from gene to product. Bailey’s research sits at the intersection of genetic engineering, cell biology, and biomanufacturing, addressing practical challenges in the production of fully processed proteins for medical and industrial use. His work exemplifies how clever molecular tools can accelerate biotherapeutic development, making him a notable figure in the field of mammalian cell engineering.
Research Focus
Key Achievements
Top Papers
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