Ann Marie Kaukonen
Papers
1
Total Citations
10
H-Index
1
About
Dr. Ann Marie Kaukonen is a specialist in laboratory automation and high-throughput screening, with a particular focus on the integration of cell-based assays onto robotic platforms. Her most cited work, a 2009 feasibility study, provides a foundational blueprint for automating three critical cellular drug screening assays—the Caspase-Glo® 3/7 apoptosis assay, the sulforhodamine B (SRB) cytotoxicity assay, and the mechanistic Caco-2 permeability protocol—on a TECAN Genesis workstation. This contribution is significant for demonstrating how to successfully transition manual, labor-intensive protocols to a fully automated, reproducible workflow, directly addressing a key bottleneck in early-stage drug discovery. By detailing the optimization and implementation process, Dr. Kaukonen’s research has helped streamline preclinical screening, enabling higher throughput and greater consistency in evaluating drug candidates. Though her citation count is modest, her work represents a practical, hands-on achievement in method development that continues to serve as a reference for researchers building automated cell-based screening systems. Her efforts underscore the critical role of automation in accelerating the drug development pipeline.
Research Focus
Key Achievements
Top Papers
- 1