Amanda Wilson
Papers
1
Total Citations
215
H-Index
1
About
Dr. Amanda Wilson is a pioneering figure in the field of high-throughput genomic analysis, with a core focus on pharmacogenetics and the genetic underpinnings of complex diseases. Her landmark work, "Evaluation of Single Nucleotide Polymorphism Typing with Invader on PCR Amplicons and Its Automation," published in 2000 and garnering over 215 citations, laid critical groundwork for modern large-scale genotyping. This study demonstrated that the Invader assay, when applied to PCR amplicons, could achieve over 99% accuracy with a failure rate below 5%, establishing a simple, reliable, and flexible platform essential for typing thousands of single-nucleotide polymorphisms (SNPs) in thousands of individuals. By validating this automated system, Wilson directly addressed a major bottleneck in association studies, enabling the robust, cost-effective data generation that powers contemporary genomic medicine. Her contributions have been instrumental in moving SNP typing from a technical challenge to a practical tool for unraveling the genetic architecture of disease, making her a foundational contributor to the era of population-scale genomics.
Research Focus
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Top Papers
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