Sarah Nutland
Papers
1
Total Citations
215
H-Index
1
About
Sarah Nutland is a leading figure in human genetics, with a career dedicated to advancing the high-throughput genotyping technologies essential for modern genomic medicine. Her foundational work centers on the development and rigorous evaluation of robust, scalable methods for single nucleotide polymorphism (SNP) typing, a critical tool for dissecting the genetic architecture of complex diseases. Her most cited paper, "Evaluation of Single Nucleotide Polymorphism Typing with Invader on PCR Amplicons and Its Automation" (2000, 215 citations), provided a landmark assessment of the Invader assay, demonstrating its potential for achieving the accuracy (>99%) and low failure rates (<5%) necessary for large-scale pharmacogenetic and disease association studies. This work was instrumental in proving that automated, flexible genotyping platforms could be deployed for projects involving thousands of individuals and millions of data points. By validating these core technologies, Nutland’s research has directly enabled the kind of powerful, population-scale studies that have since revolutionized our understanding of the genetic basis of human health and disease.
Research Focus
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Top Papers
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