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A. B. Regberg is a leading figure in planetary protection and Mars sample return science, whose work is critical to the future of human and robotic exploration of the Red Planet. Their research focuses on the intersection of astrobiology, planetary protection policy, and mission architecture, addressing the dual imperative of preserving the scientific integrity of Mars while safeguarding Earth’s biosphere. Regberg’s most influential contribution is their leadership in designing the scientific framework for the Mars Sample Return (MSR) Campaign, as detailed in their highly cited 2022 paper (29 citations), which outlines the unprecedented science benefits of returning martian samples. They have also been instrumental in identifying and closing planetary protection knowledge gaps for crewed missions, with a 2024 paper (19 citations) charting a path forward for human exploration. Notably, Regberg championed the scientific value of returning martian airfall dust (14 citations), a serendipitous yet crucial sample type for understanding atmospheric processes and future human mission risks. Their work has shaped NASA’s strategic planning, ensuring that the search for life on Mars remains a priority even as we prepare to send astronauts. With a career dedicated to enabling humanity’s next giant leap, Regberg’s research is foundational to the safe and scientifically rigorous exploration of Mars.