Yuping Tan
Papers
1
Total Citations
90
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1
About
Yuping Tan is a pioneering researcher in genomics and molecular diagnostics, best known for advancing high-throughput methods for single nucleotide polymorphism (SNP) analysis. Her landmark 1999 study, "Single nucleotide polymorphism determination using primer extension and time-of-flight mass spectrometry," with 90 citations, introduced a rapid, accurate approach that combined primer extension with MALDI-TOF mass spectrometry. This work revolutionized SNP genotyping by dramatically reducing the time and labor required for large-scale genetic analysis, enabling applications in genome mapping, identity testing, and medical diagnostics. Tan’s contributions have been instrumental in moving SNP detection from labor-intensive conventional techniques to efficient, scalable platforms, directly supporting the growth of personalized medicine and population genetics. Her innovative integration of mass spectrometry with molecular biology remains a foundational reference in the field, cited widely for its practical impact on genetic marker analysis. Through this seminal work, Tan has established herself as a key figure in the development of modern genotyping technologies, leaving a lasting imprint on how researchers approach genetic variation and its clinical applications.
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