Youhua Chen
Papers
1
Total Citations
77
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1
About
Youhua Chen is a leading researcher in radiation biodosimetry, with a primary focus on the development and automation of DNA damage detection assays. His most cited work, *"Adapting the γ-H2AX Assay for Automated Processing in Human Lymphocytes. 1. Technological Aspects"* (2010, 77 citations), established a critical methodological framework for high-throughput analysis of radiation-induced DNA double-strand breaks. By demonstrating that H2AX phosphorylation is highly linear with radiation dose, Chen validated the γ-H2AX assay as a reliable and sensitive biomarker for quantitative biodosimetry. This contribution has significantly advanced the practical application of immunofluorescence-based detection in emergency radiation triage scenarios. His work bridges fundamental radiobiology with automated laboratory processing, enabling rapid, large-scale assessment of radiation exposure in human populations. Chen’s research continues to shape the field of radiation biodosimetry, providing essential tools for both clinical and environmental radiation monitoring.
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