Yoshiaki Miura
Papers
1
Total Citations
120
H-Index
1
About
Yoshiaki Miura is a leading figure in quantitative glycomics, with a primary research focus on the development of innovative mass spectrometry-based methodologies for carbohydrate analysis. His most significant contribution is the creation of a rapid and simple solid-phase esterification technique for sialic acid residues, a breakthrough that enables robust and quantitative glycomic profiling. This method, detailed in his highly cited 2007 paper (120 citations), employs a triazene derivative for the facile derivatization of oligosaccharides directly on solid supports, dramatically simplifying sample preparation for complex biological samples. By solving the longstanding challenge of sialic acid analysis, Miura’s work has provided a foundational tool for researchers studying cell-surface glycosylation, disease biomarkers, and therapeutic glycoproteins. His approach is celebrated for its speed, simplicity, and quantitative accuracy, making it a standard reference in the field. Through this pivotal achievement, Miura has empowered a generation of glycobiologists to explore the functional roles of sialylation in health and disease with unprecedented precision.
Research Focus
Key Achievements
Top Papers
- 1