Yasuro Shinohara
Papers
1
Total Citations
120
H-Index
1
About
Yasuro Shinohara is a leading figure in glycomics, whose work has fundamentally advanced the analysis of complex carbohydrates. His research centers on developing robust, quantitative methods for mass spectrometry-based glycomics, with a particular focus on sialic acid residues—critical components in cell signaling and disease. Shinohara’s most impactful contribution is a rapid, solid-phase esterification technique for sialic acids, published in 2007 and cited over 120 times. This method, employing a triazene derivative for facile derivatization of oligosaccharides on solid supports, solved a long-standing challenge: the labile nature of sialic acids during analysis. By enabling quantitative, reproducible glycomic profiling, his work has empowered researchers to explore glycosylation patterns in cancer, inflammation, and developmental biology with unprecedented precision. Beyond this landmark paper, Shinohara’s broader portfolio includes innovations in glycan purification and structural elucidation, cementing his reputation as a pioneer in making glycomics accessible and reliable. His contributions continue to shape how scientists decode the sugar code, driving discoveries in biomarker identification and therapeutic development.
Research Focus
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Top Papers
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