Shin‐Ichiro Nishimura
Papers
1
Total Citations
120
H-Index
1
About
Shin‐Ichiro Nishimura is a leading figure in glycobiology and chemical glycoproteomics, whose work has fundamentally advanced the study of complex carbohydrates. His research centers on developing innovative chemical tools for glycomics, with a particular focus on the structural and functional analysis of sialic acid-containing glycans. Nishimura’s major contribution is the creation of rapid, solid-phase esterification methods for sialic acid residues, enabling quantitative glycomics by mass spectrometry. His seminal 2007 paper on this technique, which has garnered over 120 citations, introduced the use of 3-methyl-1-p-tolyltriazene for facile derivatization of oligosaccharides, overcoming long-standing challenges in analyzing labile sialylated structures. This work has had a profound impact on the field, providing a robust platform for high-throughput glycan profiling and biomarker discovery. Beyond this, Nishimura has pioneered chemoenzymatic synthesis strategies and glycoblotting technologies, further cementing his reputation as an innovator. His achievements have been recognized through numerous awards and leadership roles in international glycoscience communities, making him a vital resource for students and researchers seeking to understand the molecular language of glycans.
Research Focus
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Top Papers
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