Volker Kachel
Papers
2
Total Citations
54
H-Index
2
About
Volker Kachel is a pioneer in the development of high-throughput functional genomics, specializing in robotic systems for mammalian cell biology. His work bridges molecular biology and automation, enabling the systematic functional analysis of genes at an unprecedented scale. Kachel’s most-cited contributions include a groundbreaking 2006 study on a robotic system for isolating ultra-pure plasmid DNA, which achieved 27 citations by streamlining transfection-grade DNA preparation for genome-wide screens. Equally influential is his 2002 paper on a robotic high-throughput assay for isolating apoptosis-inducing genes, also with 27 citations, which introduced a transient transfection-based genetic screen to systematically identify cell death regulators in mammalian cells. This work directly addressed the growing need for functional annotation of genes from sequenced genomes. Kachel’s innovations have empowered researchers to move beyond single-gene studies to comprehensive, automated investigations of gene function, significantly accelerating the discovery of therapeutic targets. His contributions remain foundational for labs adopting robotic platforms in functional genomics and apoptosis research.
Research Focus
Key Achievements
Top Papers
- 1High-throughput isolation of ultra-pure plasmid DNA by a robotic system27 citations · 2006
- 2Robotic High-Throughput Assay for Isolating Apoptosis-Inducing Genes27 citations · 2002