Urban A. Kiernan
Arizona State University, Intrinsic LifeSciences (United States)
Papers
5
Total Citations
302
H-Index
5
About
Urban A. Kiernan is a bioanalytical researcher whose career has centered on the development and application of mass spectrometric immunoassay (MSIA) technologies for the high-throughput characterization of proteins in biological fluids. His most influential contributions have advanced the intersection of immunoaffinity extraction and mass spectrometry, enabling precise, rapid protein analysis directly from complex samples such as human plasma and blood. Kiernan's landmark work on MSIA systems, including the development of 96-well robotic platforms equipped with antibody-derivatized affinity pipet tips, transformed how researchers approach high-throughput protein quantification — work that has garnered over 75 citations. His quantitative analyses of clinically significant proteins, including β-2 microglobulin and insulin-like growth factor 1 (IGF-1), demonstrated both the versatility and rigor of MSIA methodologies, with those studies collectively cited over 160 times. His application of MALDI-TOF mass spectrometry to neonatal hemoglobin screening highlighted the technology's real-world diagnostic potential. Later work extending MSIA to resistin expression profiling using recombinant-based approaches further broadened the platform's utility. Across his body of work, Kiernan has made enduring contributions to proteomics and clinical biomarker research.
Research Focus
Key Achievements
Top Papers
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- 2Quantitative Mass Spectrometric Immunoassay of Insulin Like Growth Factor 177 citations · 2004
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