Allan L. Bieber
Papers
2
Total Citations
35
H-Index
2
About
Allan L. Bieber is a researcher whose work sits at the intersection of analytical chemistry and proteomics, with a primary focus on advancing mass spectrometry-based immunoassays. His key contributions center on the development of novel, high-sensitivity methods for protein detection and characterization, particularly through the integration of affinity capture with mass spectrometric readouts. Bieber’s most cited work, “Development of Recombinant-Based Mass Spectrometric Immunoassay with Application to Resistin Expression Profiling” (2006, 28 citations), demonstrates his innovative approach to creating a rational progression of the mass spectrometric immunoassay (MSIA) using recombinant proteins. This work specifically addressed the need for improved assays for human resistin, a hormone implicated in insulin resistance. He further expanded the toolkit for phosphoprotein analysis with his work on “Metal Ligand Affinity Pipettes and Bioreactive Alkaline Phosphatase Probes” (2004, 7 citations), where he developed a bioreactive probe that covalently binds the enzyme to the mass spectrometry target for combined affinity capture and MALDI-TOF analysis. Bieber’s contributions are notable for their focus on practical, reproducible assay development, providing researchers with refined tools for studying low-abundance proteins and post-translational modifications.
Research Focus
Key Achievements
Top Papers
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