Eric E. Niederkofler
Arizona State University, Intrinsic LifeSciences (United States)
Papers
3
Total Citations
188
H-Index
3
About
Eric E. Niederkofler is a pioneering researcher in the field of clinical proteomics and bioanalytical chemistry, with a particular focus on developing advanced mass spectrometric techniques for protein analysis in biological systems. He is best known for his foundational contributions to Mass Spectrometric Immunoassay (MSIA), a high-throughput methodology that revolutionized how proteins are extracted and characterized directly from complex biological fluids. His landmark 2001 study introducing a 96-well robotic MSIA platform for β-2 microglobulin quantification—garnering 85 citations—demonstrated the powerful potential of coupling immunoaffinity capture with mass spectrometry for clinical applications. Building on this, his 2002 work on high-throughput protein characterization using MSIA (75 citations) further established the technology's broad applicability. Niederkofler later extended this platform to incorporate recombinant protein standards, as demonstrated in his 2006 development of a recombinant-based MSIA for human resistin expression profiling, expanding the method's precision and versatility. Collectively, his contributions have significantly advanced the speed, sensitivity, and scalability of protein biomarker analysis, providing researchers and clinicians with powerful tools for disease investigation and diagnostics.
Research Focus
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Top Papers
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