Tom Brettin

Papers

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About

Tom Brettin is a leading figure in the convergence of artificial intelligence, high-performance computing, and robotic automation for scientific discovery. His visionary work centers on reimagining the laboratory as a "science factory"—a large-scale, modular, and self-driving laboratory (SDL) that integrates AI and HPC to autonomously tackle grand challenges in biology and chemistry. Brettin’s most-cited paper (26 citations) proposes a modular architecture for these factories, arguing that the scale and generality of such systems are essential for solving complex discovery problems and supporting thousands of scientists. A related paper (4 citations) further refines this concept, emphasizing how advances in AI and robotics can create computation-enabled SDLs that accelerate the pace of experimentation. Through this work, Brettin is helping to define a new paradigm for automated, data-driven research, with the potential to dramatically shorten the cycle from hypothesis to insight. His contributions are foundational for researchers interested in the future of autonomous science and the engineering of discovery at scale.