T. Quinley
Papers
2
Total Citations
192
H-Index
2
About
T. Quinley is a pioneering researcher in cell-based therapies for Duchenne muscular dystrophy (DMD), a devastating genetic muscle-wasting disorder. Their work has fundamentally advanced the experimental treatment known as myoblast transfer therapy (MTT), which aims to restore dystrophin production by injecting healthy muscle-precursor cells directly into affected muscles. In a landmark 1992 Phase II clinical trial (106 citations), Quinley demonstrated the feasibility and safety of delivering five billion normal myoblasts into the lower limbs of 21 DMD boys aged 6–14, marking one of the earliest large-scale attempts to translate cellular therapy from bench to bedside. A subsequent 1993 study (86 citations) expanded this approach to 32 boys—half nonambulatory—further establishing MTT’s potential as an experimental lower-body treatment. Quinley’s contributions are notable for their rigorous assessment of both safety and functional efficacy in a vulnerable pediatric population, laying critical groundwork for later gene and cell therapies. With over 190 citations across these core papers, Quinley’s work remains a touchstone for researchers exploring regenerative strategies for muscular dystrophy.
Research Focus
Key Achievements
Top Papers
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