Sung‐Hou Kim
Papers
1
Total Citations
38
H-Index
1
About
Sung-Hou Kim is a structural biologist whose research has made meaningful contributions to our understanding of enzyme architecture and function at the molecular level. His work has focused on protein crystallography and structural genomics, with a particular emphasis on enzymes from extremophilic organisms — microbes that thrive under harsh conditions such as high temperatures and acidity. His most recognized contribution includes the crystal structure determination of nicotinate phosphoribosyltransferase (NAPRTase) from *Thermoplasma acidophilum*, a thermoacidophilic archaeon, which has garnered 38 citations. This structural study revealed the enzyme's three-domain architecture — an N-terminal domain, a central functional domain, and a distinctive C-terminal domain — providing critical insights into the catalytic mechanisms underlying NAD biosynthesis. By elucidating how enzymes from extremophiles are organized at the atomic level, Kim's research informs both basic biochemistry and applied biotechnology, including enzyme engineering for industrial and pharmaceutical purposes. His work exemplifies how structural biology bridges molecular detail and broader biological understanding, offering a valuable resource for researchers investigating metabolic pathways and protein evolution across diverse life forms.
Research Focus
Key Achievements
Top Papers
- 1