Stephen M. Moerlein
Papers
2
Total Citations
54
H-Index
2
About
Stephen M. Moerlein is a leading figure in radiochemistry and molecular imaging, with a career dedicated to advancing the production of radiopharmaceuticals for positron emission tomography (PET). His key research areas include the automation and quality control of radiotracer synthesis, particularly for fluorine-18 and carbon-11 labeled compounds. Moerlein’s major contributions lie in improving the safety, efficiency, and purity of clinical PET agents. Notably, his 1989 paper on eliminating contaminant kryptofix 2.2.2 in the routine production of 2-[18F]fluoro-2-deoxy-d-glucose (FDG) addressed a critical impurity issue, ensuring the reliability of the world’s most widely used PET tracer, and has garnered 29 citations. He also pioneered robotic preparation methods, as demonstrated in his 2002 work on the robotic synthesis of Sodium Acetate C 11 Injection for clinical use, cited 25 times. These innovations have streamlined radiopharmaceutical manufacturing, reducing human error and enhancing reproducibility. Moerlein’s work has had a lasting impact on nuclear medicine, enabling safer, more accessible PET imaging for disease diagnosis and research.
Research Focus
Key Achievements
Top Papers
- 1
- 2Robotic preparation of Sodium Acetate C 11 Injection for use in clinical PET25 citations · 2002