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About

Stephen J. Freedland is a leading urologic oncologist whose research centers on optimizing prostate cancer surgery, particularly through comparative effectiveness studies of radical prostatectomy techniques. His work systematically evaluates outcomes between robot-assisted laparoscopic prostatectomy (RALP) and radical retropubic prostatectomy (RRP), addressing critical questions about cancer control, operative efficiency, and patient-specific factors. His most influential paper, a systematic review on the costs of radical prostatectomy (112 citations), provides essential economic context for surgical decision-making. Freedland’s research demonstrates that surgical approach significantly impacts outcomes, showing that obesity may influence positive surgical margin rates differently between RALP and RRP, and that intraoperative factors like positive end-expiratory pressure affect blood loss. Through the Shared Equal Access Regional Cancer Hospital (SEARCH) database, he has produced landmark studies on PSA recurrence-free survival and pelvic lymph node dissection utilization. His work directly informs surgical scheduling, cost containment, and personalized surgical selection in the Veterans Health System and beyond, making him a pivotal figure in evidence-based urologic oncology.